
Clinical research framework proposal for ketogenic metabolic therapy in glioblastoma.
Publication: 5 december 2024
Duraj et al. BMC Medicine (2024) 22:578.

The development of a rapid patient-derived xenograft model to predict chemotherapeutic drug sensitivity/resistance in malignant glial tumors.
Publication: 5 september 2023
Neuro Oncol. 2023 Sep 5;25(9):1605-1616. doi: 10.1093/neuonc/noad047.

A Drug-Eluting Injectable NanoGel for Localized Delivery of Anticancer Drugs to Solid Tumors.
Publication: 31 august 2023
Pharmaceutics. 2023 Aug 31;15(9):2255. doi: 10.3390/pharmaceutics15092255.

Expression of ABCB1, ABCC1 and 3 and ABCG2 in glioblastoma and their relevance in relation to clinical survival surrogates.
Publication: 15 december 2022
J Neurooncol. 2022 Dec;160(3):601-609. doi: 10.1007/s11060-022-04179-1. Epub 2022 Nov 7.

Superior Longitudinal Fasciculus: A Review of the Anatomical Descriptions With Functional Correlates.
Publication: 27 april 2022
Front Neurol. 2022 Apr 27;13:794618. doi: 10.3389/fneur.2022.794618. eCollection 2022.

Chemoattraction of Neoplastic Glial Cells with CXCL10, CCL2 and CCL11 as a Paradigm for a Promising Therapeutic Approach for Primary Brain Tumors.
Publication: 10 november 2021
Int J Mol Sci. 2021 Nov 10;22(22):12150. doi: 10.3390/ijms222212150.

Comparison of Measurement Techniques and Response Criteria for MR Imaging Follow-up in Adult Primary Central Nervous System Lymphoma.
Publication: 15 august 2021
AJNR Am J Neuroradiol. 2021 Aug;42(8):1415-1420. doi: 10.3174/ajnr.A7132. Epub 2021 Apr 29.

High-Grade Gliomas Located in the Right Hemisphere Are Associated With Worse Quality of Life.
Publication: 15 may 2021
World Neurosurg. 2021 May;149:e721-e728. doi: 10.1016/j.wneu.2021.01.111. Epub 2021 Feb 1.

Management of Primary Central Nervous System Lymphoma Using Intra-Arterial Chemotherapy With Osmotic Blood-Brain Barrier Disruption: Retrospective Analysis of the Sherbrooke Cohort.
Publication: 20 january 2021
Front Oncol. 2021 Jan 20;10:543648. doi: 10.3389/fonc.2020.543648. eCollection 2020.

Successful Management of Glioblastoma Chemotherapy-Associated Dysgeusia with Gabapentin.
Publication: 15 november 2020
Can J Neurol Sci. 2020 Nov;47(6):839-841. doi: 10.1017/cjn.2020.115. Epub 2020 Jun 5.

Three-Dimensional Nuclear Telomere Profiling as a Biomarker for Recurrence in Oligodendrogliomas: A Pilot Study.
Publication: 12 november 2020
Int J Mol Sci. 2020 Nov 12;21(22):8539. doi: 10.3390/ijms21228539.

Pharmacological Modulation of Blood-Brain Barrier Permeability by Kinin Analogs in Normal and Pathologic Conditions.
Publication: 29 september 2020
Pharmaceuticals (Basel). 2020 Sep 29;13(10):279. doi: 10.3390/ph13100279.

Letter: The Risk of COVID-19 Infection During Neurosurgical Procedures: A Review of Severe Acute Respiratory Distress Syndrome Coronavirus 2 (SARS-CoV-2) Modes of Transmission and Proposed Neurosurgery-Specific Measures for Mitigation.
Publication: 1 august 2020
Neurosurgery. 2020 Aug 1;87(2):E178-E185. doi: 10.1093/neuros/nyaa157.

The role of diffusion tractography in refining glial tumor resection.
Publication: 15 may 2020
Brain Struct Funct. 2020 May;225(4):1413-1436. doi: 10.1007/s00429-020-02056-z. Epub 2020 Mar 16.

Mobile Applications in Neurosurgery: A Systematic Review, Quality Audit, and Survey of Canadian Neurosurgery Residents.
Publication: 15 july 2019
World Neurosurg. 2019 Jul;127:e1026-e1038. doi: 10.1016/j.wneu.2019.04.035. Epub 2019 Apr 10.

Drug Delivery Technology to the CNS in the Treatment of Brain Tumors - The Sherbrooke Experience.
Publication: 27 may 2019
Pharmaceutics. 2019 may 27;11(5):248. doi:10.3390/pharmaceutics11050248.

Liposomal formulations of carboplatin injected by convection-enhanced delivery increases the median survival time of F98 glioma bearing rats.
Publication: 5 october 2018
J Nanobiotechnology. 2018 Oct 5;16(1):77. doi: 10.1186/s12951-018-0404-8.

Chronic Subdural Hematoma: Toward a New Management Paradigm for an Increasingly Complex Population.
Publication: 15 august 2018
J Neurotrauma. 2018 Aug 15;35(16):1882-1885. doi: 10.1089/neu.2018.5872.

Recognition of white matter bundles using local and global streamline-based registration and clustering.
Publication: 15 april 2018
Neuroimage. 2018 Apr 15;170:283-295. doi: 10.1016/j.neuroimage.2017.07.015. Epub 2017 Jul 13.

Differential Expression and Clinical Significance of Transforming Growth Factor-Beta Isoforms in GBM Tumors.
Publication: 8 april 2018
Int J Mol Sci. 2018 Apr 8;19(4):1113. doi: 10.3390/ijms19041113.

Smartphone usage patterns by Canadian neurosurgery residents: a national cross-sectional survey.
Publication: 25 march 2018
World Neurosurg. 2018 Mar;111:e465-e470. doi: 10.1016/j.wneu.2017.12.089. Epub 2017 Dec 23.

Demographics, Interests, and Quality of Life of Canadian Neurosurgery Residents.
Publication: 15 march 2018
Can J Neurol Sci. 2018 Mar;45(2):214-220. doi: 10.1017/cjn.2017.263. Epub 2017 Dec 14.

On the Origin of Individual Functional Connectivity Variability: The Role of White Matter Architecture.
Publication: 15 october 2017
Brain Connect. 2017 Oct;7(8):491-503. doi: 10.1089/brain.2017.0539.

Active delineation of Meyer's loop using oriented priors through MAGNEtic tractography (MAGNET).
Publication: 15 january 2017
Hum Brain Mapp. 2017 Jan;38(1):509-527. doi: 10.1002/hbm.23399. Epub 2016 Sep 20.

Infiltration of F98 glioma cells in Fischer rat brain is temporarily stimulated by radiation.
Publication: 15 august 2016
Int J Radiat Biol. 2016 Aug;92(8):444-50. doi: 10.1080/09553002.2016.1175682. Epub 2016 Apr 28.

Exploratory study of the effect of brain tumors on the default mode network.
Publication: 15 july 2016
J Neurooncol. 2016 Jul;128(3):437-44. doi: 10.1007/s11060-016-2129-6. Epub 2016 Apr 18.

Convection-enhancement delivery of liposomal formulation of oxaliplatin shows less toxicity than oxaliplatin yet mayntains a similar median survival time in F98 glioma-bearing rat model.
Publication: 15 june 2016
Invest New Drugs. 2016 Jun;34(3):269-76. doi: 10.1007/s10637-016-0340-0. Epub 2016 Mar 9.

TBI prognosis calculator: A mobile application to estimate mortality and morbidity following traumatic brain injury.
Publication: 15 march 2016
Clin Neurol Neurosurg. 2016 Mar;142:48-53. doi: 10.1016/j.clineuro.2016.01.021. Epub 2016 Jan 16.

Chloroquine inhibits the malignant phenotype of glioblastoma partially by suppressing TGF-beta.
Publication: 15 october 2015
Invest New Drugs. 2015 Oct;33(5):1020-31. doi: 10.1007/s10637-015-0275-x. Epub 2015 Aug 15.

Seeing More by Showing Less: Orientation-Dependent Transparency Rendering for Fiber Tractography Visualization.
Publication: 7 october 2015
PLoS One. 2015 Oct 7;10(10):e0139434. doi: 10.1371/journal.pone.0139434. eCollection 2015.

Cyclooxygenase-2 inhibitor prevents radiation-enhanced infiltration of F98 glioma cells in brain of Fischer rat.
Publication: 15 august 2015
Int J Radiat Biol. 2015 Aug;91(8):624-33. doi: 10.3109/09553002.2015.1043756. Epub 2015 May 21.

3D interactive tractography-informed resting-state fMRI connectivity.
Publication: 15 august 2015
Front Neurosci. 2015 Aug 11;9:275. doi: 10.3389/fnins.2015.00275. eCollection 2015.

Chemotherapy Delivery Strategies to the Central Nervous System: Neither Optional nor Superfluous.
Publication: 15 june 2015
Curr Cancer Drug Targets. 2015;15(9):752-68. doi: 10.2174/1568009615666150616123548.

Convection-enhancement delivery of platinum-based drugs and Lipoplatin™ to optimize the concomitant effect with radiotherapy in F98 glioma rat model.
Publication: 15 june 2015
Invest New Drugs. 2015 Jun;33(3):555-63. doi: 10.1007/s10637-015-0228-4. Epub 2015 Mar 18.

Transforming growth factor-beta and its implication in the malignancy of gliomas.
Publication: 10 march 2015
Target Oncol. 2015 Mar;10(1):1-14. doi: 10.1007/s11523-014-0308-y. Epub 2014 Mar 5.

Alterations in Epigenetic Markers Related to 5-Hydroxymethylcytosine in Brain Cancer.
Publication: 15 november 2014
Free Radical Biology and Medicine supplement 1 (76), s134-s135.

Intra-arterial carboplatin as a salvage strategy in the treatment of recurrent glioblastoma multiforme.
Publication: 15 september 2014
J Neurooncol. 2014 Sep;119(2):397-403. doi: 10.1007/s11060-014-1504-4. Epub 2014 Jun 20.

Structural network underlying visuospatial imagery in humans.
Publication: 15 july 2014
Cortex. 2014 Jul;56:85-98. doi: 10.1016/j.cortex.2013.02.004. Epub 2013 Feb 17.

Real-time multi-peak tractography for instantaneous connectivity display.
Publication: 30 may 2014
Front Neuroinform. 2014 May 30;8:59. doi: 10.3389/fninf.2014.00059. eCollection 2014.

Impact of drug size on brain tumor and brain parenchyma delivery after a blood-brain barrier disruption.
Publication: 15 may 2014
J Cereb Blood Flow Metab. 2014 May;34(5):820-6. doi: 10.1038/jcbfm.2014.14. Epub 2014 Feb 12.

A new der(1;7)(q10;p10) leading to a singular 1p loss in a case of glioblastoma with oligodendroglioma component.
Publication: 15 april 2014
Neuropathology. 2014 Apr;34(2):170-8. doi: 10.1111/neup.12060. Epub 2013 Sep 30.

Optimization of the route of platinum drugs administration to optimize the concomitant treatment with radiotherapy for glioblastoma implanted in the Fischer rat brain.
Publication: 15 december 2013
J Neurooncol. 2013 Dec;115(3):365-73. doi: 10.1007/s11060-013-1238-8. Epub 2013 Sep 13.

Effects of surgical resection on the evolution of quality of life in newly diagnosed patients with glioblastoma: a report on 19 patients surviving to follow-up.
Publication: 29 october 2013
Curr Med Res Opin. 2013 Oct;29(10):1307-13. doi: 10.1185/03007995.2013.823858. Epub 2013 Jul 30.

Dual kinin B1 and B2 receptor activation provides enhanced blood-brain barrier permeability and anticancer drug delivery into brain tumors.
Publication: 14 september 2013
Cancer Biol Ther. 2013 Sep;14(9):806-11. doi: 10.4161/cbt.25327. Epub 2013 Jun 14.

Tractography in the study of the human brain: a neurosurgical perspective.
Publication: 15 november 2012
Can J Neurol Sci. 2012 Nov;39(6):747-56. doi: 10.1017/s0317167100015560.

Does extent of resection impact survival in patients bearing glioblastoma?
Publication: 15 september 2012
Can J Neurol Sci. 2012 Sep;39(5):632-7. doi: 10.1017/s0317167100015377.

Glioblastoma treatment: bypassing the toxicity of platinum compounds by using liposomal formulation and increasing treatment efficiency with concomitant radiotherapy.
Publication: 1 september 2012
Int J Radiat Oncol Biol Phys. 2012 Sep 1;84(1):244-9. doi: 10.1016/j.ijrobp.2011.10.054. Epub 2012 Jan 26.

Infiltration of glioma cells in brain parenchyma stimulated by radiation in the F98/Fischer rat model.
Publication: 15 august 2012
Int J Radiat Biol. 2012 Aug;88(8):565-74. doi: 10.3109/09553002.2012.692495. Epub 2012 Jun 19.

A new method of quantitatively assessing the opening of the blood-brain barrier in murine animal models.
Publication: 15 june 2012
J Neurosci Methods. 2012 Jun 15;207(2):125-9. doi: 10.1016/j.jneumeth.2012.03.012. Epub 2012 Apr 12.

Induction of selective blood-tumor barrier permeability and macromolecular transport by a biostable kinin B1 receptor agonist in a glioma rat model.
Publication: 21 may 2012
PLoS One. 2012;7(5):e37485. doi: 10.1371/journal.pone.0037485. Epub 2012 May 21.

The blood-brain barrier: its influence in the treatment of brain tumors metastases.
Publication: 12 march 2012
Curr Cancer Drug Targets. 2012 Mar;12(3):247-59. doi: 10.2174/156800912799277511.

The Max b-HLH-LZ can transduce into cells and inhibit c-Myc transcriptional activities.
Publication: 22 february 2012
PLoS One. 2012;7(2):e32172. doi: 10.1371/journal.pone.0032172. Epub 2012 Feb 22.

Safety and efficacy of Gamma Knife surgery for brain metastases in eloquent locations.
Publication: 15 december 2010
J Neurosurg. 2010 Dec;113 Suppl:79-83.

Blood-brain barrier disruption in the treatment of brain tumors.
Publication: 12 november 2010
Methods Mol Biol. 2011:686:447-63. doi: 10.1007/978-1-60761-938-3_23.

Uptake and Intracellular Release Kinetics of Liposome Formulations in Glioma Cells.
Publication: 16 august 2010
Int J Pharm. 2010 Aug 16;395(1-2):251-9. doi: 10.1016/j.ijpharm.2010.05.017. Epub 2010 Jun 1.

Brain tumor headaches: from bedside to bench.
Publication: 15 august 2010
Neurosurgery. 2010 Aug;67(2):459-66. doi: 10.1227/01.NEU.0000372092.96124.E6.

Quality of life in neurooncology--age matters.
Publication: 15 august 2010
J Neurosurg. 2010 Aug;113(2):325-32. doi: 10.3171/2010.2.JNS091707.

Concomitant treatment of F98 glioma cells with new liposomal platinum compounds and ionizing radiation.
Publication: 15 april 2010
J Neurooncol. 2010 Apr;97(2):187-93. doi: 10.1007/s11060-009-0011-5. Epub 2009 Sep 17.

Selective tumor blood-brain barrier opening with the kinin B2 receptor agonist [Phe(8)psi(CH(2)NH)Arg(9)]-BK in a F98 glioma rat model: an MRI study.
Publication: 15 april 2010
Neuropeptides. 2010 Apr;44(2):177-85. doi: 10.1016/j.npep.2009.12.009. Epub 2010 Jan 18.

Three-dimensional nuclear telomere architecture is associated with differential time to progression and overall survival in glioblastoma patients.
Publication: 15 february 2010
Neoplasia. 2010 Feb;12(2):183-91. doi: 10.1593/neo.91752.

EGF receptor inhibitors in the treatment of glioblastoma multiform: old clinical allies and newly emerging therapeutic concepts.
Publication: 25 december 2009
Eur J Pharmacol. 2009 Dec 25;625(1-3):23-30. doi: 10.1016/j.ejphar.2009.10.010. Epub 2009 Oct 18.

Is the 1p/19q deletion a diagnostic marker of oligodendrogliomas?
Publication: 25 october 2009
Cancer Genet Cytogenet. 2009 Oct;194(1):12-22. doi: 10.1016/j.cancergencyto.2009.05.004.

Real-time monitoring of gadolinium diethylenetriamine penta-acetic acid during osmotic blood-brain barrier disruption using magnetic resonance imaging in normal wistar rats.
Publication: 15 august 2009
Neurosurgery. 2009 Aug;65(2):344-50; discussion 350-1. doi: 10.1227/01.NEU.0000349762.17256.9E.

Polymer gel in rat skull to assess the accuracy of a new rat stereotactic device for use with the Gamma Knife.
Publication: 15 june 2009
Acta Neurochir (Wien). 2009 Jun;151(6):677-83; discussion 683-4. doi: 10.1007/s00701-009-0298-1. Epub 2009 Apr 18.

Development of a concise QOL questionnaire for brain tumor patients.
Publication: 15 may 2009
Can J Neurol Sci. 2009 May;36(3):340-8. doi: 10.1017/s0317167100007095.

Tumor bed radiosurgery after resection of cerebral metastases.
Publication: 15 april 2008
Neurosurgery. 2008 Apr;62(4):817-23; discussion 823-4. doi: 10.1227/01.neu.0000316899.55501.8b.

Recent advances in blood-brain barrier disruption as a CNS delivery strategy.
Publication: 18 march 2008
AAPS J. 2008;10(1):166-77. doi: 10.1208/s12248-008-9018-7. Epub 2008 Mar 18.

Intraarterial chemotherapy and osmotic blood-brain barrier disruption for patients with embryonal and germ cell tumors of the central nervous system.
Publication: 1 february 2008
Cancer. 2008 Feb 1;112(3):581-8. doi: 10.1002/cncr.23221.

Chemotherapy and delivery in the treatment of primary brain tumors.
Publication: 2 september 2007
Curr Clin Pharmacol. 2007 Sep;2(3):197-211. doi: 10.2174/157488407781668767.

Standardization and detailed characterization of the syngeneic Fischer/F98 glioma model.
Publication: 15 august 2007
Can J Neurol Sci. 2007 Aug;34(3):296-306. doi: 10.1017/s0317167100006715.

Enhanced chemotherapy delivery by intraarterial infusion and blood-brain barrier disruption in the treatment of cerebral metastasis.
Publication: 15 february 2007
Cancer. 2007 Feb 15;109(4):751-60. doi: 10.1002/cncr.22450.

Osmotic blood-brain barrier disruption chemotherapy for diffuse pontine gliomas.
Publication: 15 may 2006
J Neurooncol. 2006 May;77(3):279-84. doi: 10.1007/s11060-005-9038-4. Epub 2005 Nov 29.

The role of chemotherapy in the treatment of malignant astrocytomas.
Publication: 15 may 2006
Can J Neurol Sci. 2006 May;33(2):127-40. doi: 10.1017/s0317167100004881.

MR-pathological comparison in F98-Fischer glioma model using a human gantry.
Publication: 15 february 2006
Can J Neurol Sci. 2006 Feb;33(1):86-91. doi: 10.1017/s0317167100004753.

Intracranial invasion of a basal cell carcinoma of the scalp.
Publication: 15 november 2005
Can J Neurol Sci. 2005 Nov;32(4):546-8. doi: 10.1017/s0317167100004595.

Enhanced chemotherapy delivery by intraarterial infusion and blood-brain barrier disruption in malignant brain tumours.
Publication: 15 june 2005
Cancer. 2005 Jun 15;103(12):2606-15. doi: 10.1002/cncr.21112.

Neuronal injuries induced by perinatal hypoxic-ischemic insults are potentiated by prenatal exposure to lipopolysaccharide: animal model for perinatally acquired encephalopathy.
Publication: 15 march 2005
Dev Neurosci 2005;27:134–142.

La barrière hémato-encéphalique : un facteur clé en Neuro-oncologie.
(The blood-brain barrier should not be underestimated in neuro-oncology.)
Publication: 15 may 2004
Rev Neurol (Paris). 2004 May;160(5 Pt 1):523-32. doi: 10.1016/s0035-3787(04)70981-9.

A blood-brain barrier disruption model eliminating the hemodynamic effect of ketamine.
Publication: 15 may 2004
Can J Neurol Sci. 2004 May;31(2):248-53. doi: 10.1017/s0317167100053890.

Technical modification in the intracarotid chemotherapy and osmotic blood-brain barrier disruption procedure to prevent the relapse of carboplatin-induced orbital pseudotumor.
Publication: 15 may 2004
AJNR Am J Neuroradiol. 2004 May;25(5):830-4.

Altering the properties of the blood-brain barrier: disruption and permeabilization.
Publication: 15 december 2003
Prog Drug Res. 2003;61:125-54. doi: 10.1007/978-3-0348-8049-7_5.

Chemotherapeutic dose intensification for treatment of malignant brain tumors: recent developments and future directions.
Publication: 15 may 2002
Curr Neurol Neurosci Rep. 2002 May;2(3):216-24. doi: 10.1007/s11910-002-0080-8.

Ki-67: a prognostic factor for low-grade glioma?
Publication: 15 march 2002
Int J Radiat Oncol Biol Phys. 2002 Mar 15;52(4):996-1001. doi: 10.1016/s0360-3016(01)02720-1.